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Cancer
Editor-in-Chief: Suresh S. Ramalingam, MD
© American Cancer Society
About This Journal
Cancer, an international interdisciplinary journal of the American Cancer Society, publishes high-impact, peer-reviewed original articles and solicited content on the latest clinical research findings. Each issue of Cancer strives to be comprehensive, spanning the breadth of oncology disciplines and providing something for everyone involved in cancer research, risk reduction, treatment, and patient care.
The goal of Cancer is to publish research aligned with the American Cancer Society’s mission to save lives and move us closer to a world without cancer. Cancer is primarily interested in quality papers focused in the following research areas:
- Risk reduction and early detection
- Novel approaches to treatment
- Large randomized clinical trial results
- Understanding psychosocial aspects of care
- Moving toward a tobacco-free society
- Addressing and reducing health disparities
Featured Content
Why Submit to Cancer?
Maximum reach, high impact, no fees. These are just a few of the benefits for authors who submit their research findings to Cancer.
Dr. Suresh Ramalingam Selected as Editor-in-Chief of Cancer
Cancer is pleased to announce Suresh S. Ramalingam, MD has been selected as the new Editor-in-Chief starting in July 2021.
Learn More.
COVID-19 and Oncology Special Collection
Access a growing collection of articles addressing the challenges of COVID-19 from the American Cancer Society Journals.
Women in limited-resource settings continue to face significant obstacles to receiving timely, effective, and high-quality breast cancer care. The Breast Healthcare Global Initiative Sixth Global Summit has developed a series of evidence-based phased-implementation pathways to translate resource-stratified guidelines into practice, including a series of prerequisites required for their stepwise implementation and monitoring.
Research on cancer survivorship is more important than ever. Due to rising population growth and improved diagnostics, the number of cancer survivors is increasing. We have curated a special collection of the latest survivorship research from The American Cancer Society Journals. Learn more.
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The Annual Report to the Nation on the Status of Cancer provides a regular update on cancer incidence (new cases) and mortality (death) rates. The Centers for Disease Control and Prevention (CDC), American Cancer Society (ACS), National Cancer Institute (NCI), and North American Association of Central Cancer Registries (NAACCR) have worked together since 1998 to produce this report. The latest Annual Report to the Nation on the Status of Cancer finds that for all cancer sites combined, cancer death rates continued to decline in men, women, adolescents, and children in the United States from 2001 to 2017.
Pain in long‐term survivors of childhood cancer: A systematic review of the current state of knowledge and a call to action from the Children's Oncology Group
A conceptual model of the factors associated with pain in survivors of childhood cancer.
Abstract | Full Article (HTML) | PDF
Defining the role of neoadjuvant systemic therapy in high‐risk retroperitoneal sarcoma: A multi ‐ institutional study from the Transatlantic Australasian Retroperitoneal Sarcoma Working Group
Example of a high‐risk retroperitoneal sarcoma. Cross‐sectional imaging studies demonstrate potential involvement of multiple organs and critical structures.
Abstract | Full Article (HTML) | PDF
Immune responses in genomically simple SWI/SNF–deficient cancers
Potential mechanisms leading to an innate immune response against SWI/SNF‐deficient tumor cells.
Aggressive myoepithelial carcinoma with EWSR1‐POU5F1 fusion highly responsive to Ewing sarcoma combination chemotherapy
Coronal and transverse sections of computed tomography scans of the abdomen and pelvis.
Morphologic and molecular analysis of early‐onset gastric cancer
A spectrum of mutations and copy number alterations is illustrated.
From Dr. Ramalingam
Cancer, among the oldest and most prestigious oncology journals, is well positioned to bring the best of science to the broadest audience with a strong focus on featuring research that directly affects the lives of patients with cancer.
Read Dr. Ramalingam’s latest editorial.
CancerScope
Annual Report to the Nation
The American Cancer Society (ACS), the Centers for Disease Control and Prevention (CDC), the National Cancer Institute (NCI), and the North American Association of Central Cancer Registries (NAACCR) collaborate to provide annual updates on cancer occurrence and trends in the United States.
The Annual Report to the Nation (ARN) on the Status of Cancer is now available. Click below to access these articles:
Articles
Treatment patterns and outcomes of palliative systemic therapy in patients with salivary duct carcinoma and adenocarcinoma, not otherwise specified
- 18 October 2021
Abstract
Adding systemic therapy to local therapy may improve outcomes of patients with locoregionally advanced SDC or adeno-NOS. Response to palliative chemotherapy is limited and underscores a clinical unmet need for patients with these diseases.
Perioperative circulating tumor DNA as a potential prognostic marker for operable stage I to IIIA non–small cell lung cancer
- 18 October 2021
Abstract
Perioperative circulating tumor DNA (ctDNA) analyses identify disease recurrence earlier than routine radiologic imaging. ctDNA analyses can detect minimal residual disease for resectable non–small cell lung cancer and thus can facilitate early intervention.
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Annual Report to the Nation on the Status of Cancer, part I: National cancer statistics
- 2785-2800
- 22 May 2018
Abstract
The National Cancer Institute, the Centers for Disease Control and Prevention, the American Cancer Society, and the North American Association of Central Cancer Registries collaborate annually to provide updated information about cancer occurrence and trends in the United States. Part I of this year's report highlights the continued declines in cancer incidence and mortality among men and in cancer mortality among women. It notes that differences in rates and trends by race and ethnic group remain, and progress in reducing cancer mortality has not occurred for all sites.See also pages 2801-14.
Osteosarcoma incidence and survival rates from 1973 to 2004
- 1531-1543
- 5 February 2009
Abstract
This comprehensive, population-based description of osteosarcoma identified important differences in incidence, survival, pathologic subtype, and anatomic site among age groups and quantified the impact of osteosarcoma in Paget disease or as a second cancer on incidence and mortality rates. These findings may have implications for understanding the biology and epidemiology of osteosarcoma.
Percent free prostate‐specific antigen (PSA) is an accurate predictor of prostate cancer risk in men with serum PSA 2.5 ng/mL and lower
- Cancer
- 2695-2703
- 3 November 2008
Abstract
The risk of prostate cancer is evident in patients with prostate-specific antigen (PSA) ≤2.5 ng/mL. Percent free PSA can accurately predict the prevalence of prostate cancer at prostate biopsy in these individuals.
MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy
- Cancer
- 4423-4431
- 28 July 2020
Abstract
The Multinational Association of Supportive Care in Cancer and the International Society of Oral Oncology developed clinical practice guidelines for the management of mucositis, with the first edition published in 2004 and periodically updated. This summary presents the 2019/2020 guidelines update, which is based on a systematic review, and generates a tool that will help clinicians to select evidence-based interventions.
Annual report to the nation on the status of cancer, part I: National cancer statistics
- Cancer
- 2225-2249
- 12 March 2020
Abstract
The Centers for Disease Control and Prevention, the American Cancer Society, the National Cancer Institute, and the North American Association of Central Cancer Registries collaborate to provide annual updates on cancer occurrence and trends in the United States and to address a special topic of interest. Part I of this report focuses on national cancer statistics, and part II characterizes progress in achieving select Healthy People 2020 objectives related to 4 common cancers.
Intravenous methotrexate as central nervous system (CNS) prophylaxis is associated with a low risk of CNS recurrence in high‐risk patients with diffuse large B‐cell lymphoma
- Cancer
- 4283-4290
- 3 September 2010
Abstract
Central nervous system (CNS) disease recurrence in patients with diffuse large B-cell lymphoma is a rare but devastating event. This article reports that intravenous methotrexate can be safely administered concurrently with cyclophosphamide, doxorubicin, vincristine, and prednisone with rituximab (R-CHOP) and is associated with decreased risk of CNS recurrence in high-risk patients.
Impact of the coronavirus disease 2019 (COVID‐19) pandemic on pediatric oncology care in the Middle East, North Africa, and West Asia region: A report from the Pediatric Oncology East and Mediterranean (POEM) group
- Cancer
- 4235-4245
- 10 July 2020
Abstract
The response to the coronavirus disease 2019 (COVID-19) pandemic has led to significant alterations in access to care for children with cancer. Interventions are needed to mitigate the effects on life-threatening diseases requiring immediate and uninterrupted therapy, such as childhood cancer.
Recent issues
Latest news
More from Cancer
- Why Submit to Cancer
- COVID-19 and Oncology Special Collection
- Adolescent and Young Adult Cancer Virtual Issue
- Editor's Picks Collection: Cancer Disparities Research
- Colorectal Cancer Research Collection
- Published Cancer Supplements
- Supplements: Policy and Instructions
- Breast Cancer Research Virtual Issue
- Landmarks in History of Cancer
- Cancer Survivorship Research Collection
- CancerScope Articles
- CME for Reviewers
- 2020 Thank You to Reviewers
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