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About This Journal
Cancer, an international interdisciplinary journal of the American Cancer Society, publishes high-impact, peer-reviewed original articles and solicited content on the latest clinical research findings. Each issue of Cancer strives to be comprehensive, spanning the breadth of oncology disciplines and providing something for everyone involved in cancer research, risk reduction, treatment, and patient care.
The goal of Cancer is to publish research aligned with the American Cancer Society’s mission to save lives and move us closer to a world without cancer. Cancer is primarily interested in quality papers focused in the following research areas:
- Risk reduction and early detection
- Novel approaches to treatment
- Large randomized clinical trial results
- Understanding psychosocial aspects of care
- Moving toward a tobacco-free society
- Addressing and reducing health disparities
Featured Content
From Dr. Ramalingam
Celebrating 75 years of publication, Cancer continues to serve as a beacon for scientific research that is fundamental to achieving cures for cancer. Heading into the future, the journal will continue to maintain its unique identity and strive to bring the best of science to the broadest of the audience.
Top Advances of the Year
Cancer is pleased to present “Top Advances of the Year,” a new series of articles that highlight cutting-edge advances in cancer research for specific organ-site cancers. These articles reflect the opinions of the leaders in the respective areas and are intended to keep the readers apprised on major progress. The authors provide a succinct review on the top advances and their key “take-home messages” from the specific studies discussed; the readers are referred to the original articles for additional details.
Explore the latest Top Advances of the Year articles here.Annual Report to the Nation
The American Cancer Society (ACS), the Centers for Disease Control and Prevention (CDC), the National Cancer Institute (NCI), and the North American Association of Central Cancer Registries (NAACCR) collaborate to provide annual updates on cancer occurrence and trends in the United States.
Parts 1 and 2 of Annual Report to the Nation on the Status of Cancer are now available. Click below to access the articles.
Part 1: National cancer statistics
Part 2: Early assessment of the COVID-19 pandemic’s impact on cancer diagnosis
CancerScope
CancerScope: Oncology Issues in Focus is a news section that offers readers timely information on events, public policy analysis, topical issues, and personalities.
First person profile: Jedd Wolchok, MD
Click here to read this article | Click here to download the PDF
Cancer Complimentary
Enjoy a free-to-read article from the latest issue of Cancer.
Efficacy and safety of pralsetinib in patients with advanced RET fusion‐positive non–small cell lung cancer
Modifiable risk‐attributable and age‐related burden of lung cancer in China, 1990–2019
Systematic review and meta-analysis: Prognostic impact of time from diagnosis to treatment in patients with acute myeloid leukemia
Articles
Pediatric cancer incidence among individuals with overgrowth syndromes and overgrowth features: A population‐based assessment in seven million children
-  3 October 2023
Abstract
Children with either overgrowth syndromes or features are at a significantly increased risk for childhood cancer. Results from this study may ultimately be used to guide recommendations for cancer surveillance in children with overgrowth syndromes/features and may also inform future research into cancer etiology.
What are the most effective exercise, physical activity and dietary interventions to improve body composition in women diagnosed with or at high‐risk of breast cancer? A systematic review and network meta‐analysis
-  3 October 2023
Abstract
Exercise, nutrition, and weight management guidelines are widely recognized; however, no recommendations have specifically focused on improving body composition in breast cancer patients. This review highlights the most effective interventions to improve body composition and assist in weight management for breast cancer patients during or following treatment.
Effect of preoperative programmed death‐1 or programmed death ligand‐1 immune check point inhibition on complications after surgery for primary head and neck cancer
-  3 October 2023
Abstract
In this study, nICI did not increase the risk of overall complications after adjusting for important confounders. Definitive surgery can be conducted safely after nICI.
The ever‐increasing importance of cancer as a leading cause of premature death worldwide
-  3029-3030
-  4 June 2021
Abstract
Cardiovascular disease and cancer are now the leading causes of premature death in the majority of countries worldwide, and cancer is likely to surpass cardiovascular disease as the leading causes of death at ages 30-70 in most countries over the course of this century. Governments must factor in these transitions in formulating and implementing their cancer and noncommunicable disease plans and tailor cost-effective measures to the local disease profile.
Osteosarcoma incidence and survival rates from 1973 to 2004
-  1531-1543
-  5 February 2009
Abstract
This comprehensive, population-based description of osteosarcoma identified important differences in incidence, survival, pathologic subtype, and anatomic site among age groups and quantified the impact of osteosarcoma in Paget disease or as a second cancer on incidence and mortality rates. These findings may have implications for understanding the biology and epidemiology of osteosarcoma.
Annual report to the nation on the status of cancer, part 1: National cancer statistics
- Cancer
-  4251-4284
-  27 October 2022
Abstract
The American Cancer Society, the Centers for Disease Control and Prevention, the National Cancer Institute, and the North American Association of Central Cancer Registries collaborate annually to provide updated information about cancer occurrence and trends in the United States. Part 1 of this year's report provides information on cancer incidence and mortality rates and trends for males and females and by race/ethnicity for common cancer sites, with an in-depth look at pancreatic cancer.
Risk of prostate cancer and death after benign transurethral resection of the prostate—A 20‐year population‐based analysis
- Cancer
-  3674-3680
-  17 August 2022
Abstract
Men with low prostate-specific antigen (PSA) levels and a benign transurethral resection of the prostate can be reassured about their cancer risk and do not need to be monitored differently than any other men, but patients with high PSA levels should be considered for further follow-up. This study's findings add to a body of literature suggesting that normal histology from the prostate entails a low risk of death from the disease.
MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy
- Cancer
-  4423-4431
-  28 July 2020
Abstract
The Multinational Association of Supportive Care in Cancer and the International Society of Oral Oncology developed clinical practice guidelines for the management of mucositis, with the first edition published in 2004 and periodically updated. This summary presents the 2019/2020 guidelines update, which is based on a systematic review, and generates a tool that will help clinicians to select evidence-based interventions.
The BiTE (bispecific T‐cell engager) platform: Development and future potential of a targeted immuno‐oncology therapy across tumor types
- Cancer
-  3192-3201
-  13 May 2020
Abstract
This review provides an overview of immuno-oncology therapies and those in development. It specifically focuses on bispecific T-cell engager (BiTE) technology, its mechanism of action, types of cancer in which it has had success, half-life-extended BiTE molecules, and their potential as an off-the-shelf, targeted immunotherapy.
The ever‐increasing importance of cancer as a leading cause of premature death worldwide
- Cancer
-  3029-3030
-  4 June 2021
Abstract
Cardiovascular disease and cancer are now the leading causes of premature death in the majority of countries worldwide, and cancer is likely to surpass cardiovascular disease as the leading causes of death at ages 30-70 in most countries over the course of this century. Governments must factor in these transitions in formulating and implementing their cancer and noncommunicable disease plans and tailor cost-effective measures to the local disease profile.
Recent issues
- IssueVolume 129, Issue S19
Breast Health Equity Along the Cancer Care Continuum: A Collaborative Grant Initiative
3079-31811 October 2023